Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538956 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL7537410 | 0.85 | MAPT (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL22892932 | 0.82 | KDR (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7537261 | 0.81 | F10 (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL7532612 | 0.81 | HTT (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7537216 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7533744 | 0.80 | SLC20A2 (0.58) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7538052 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL7533699 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL7538011 | 0.77 | LMNA (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |