Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538011 | 0.96 | LMNA (0.55) | ALDH1A1TSHRPOLBKDM4EDHODH | |
| SCHEMBL7537030 | 0.87 | MAPT (0.53) | ALDH1A1KDM4EKMT2AMEN1GRM4 | |
| SCHEMBL7533744 | 0.87 | SLC20A2 (0.58) | ALDH1A1TSHRPOLBKMT2AMEN1 | |
| SCHEMBL7533306 | 0.87 | KMT2A (0.54) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL7538052 | 0.87 | SMN1; SMN2 (0.56) | ALDH1A1POLBKDM4EDHODHKMT2A | |
| SCHEMBL7533699 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1POLBKDM4EKMT2AMEN1 | |
| SCHEMBL7533017 | 0.84 | LMNA (0.53) | ALDH1A1TSHRPOLBKDM4EKMT2A | |
| SCHEMBL7537988 | 0.84 | LMNA (0.61) | ALDH1A1TSHRPOLBKDM4EKMT2A | |
| SCHEMBL7539008 | 0.83 | LMNA (0.60) | ALDH1A1TSHRPOLBKDM4EKMT2A | |
| SCHEMBL7531858 | 0.82 | KMT2A (0.55) | ALDH1A1TSHRPOLBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |