Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340302 | 0.82 | AKR1B1 (0.33) | NR4A2TSHRALDH1A1THRBHSD17B10 | |
| SCHEMBL18072719 | 0.75 | APAF1 (0.41) | NR4A2L3MBTL1 | |
| SCHEMBL18052196 | 0.75 | APAF1 (0.41) | NR4A2L3MBTL1 | |
| SCHEMBL9236840 | 0.71 | HSD17B10 (0.35) | ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9240860 | 0.70 | AKR1B1 (0.36) | ALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL31494692 | 0.69 | NR4A2 (0.39) | NR4A2CA12CA1CA2CA9 | |
| SCHEMBL10714867 | 0.68 | — | — | |
| Water SCHEMBL15121340 | 0.68 | SLC22A4 (0.34) | — | |
| SCHEMBL7534419 | 0.67 | TBXAS1 (0.45) | TSHR | |
| SCHEMBL20677353 | 0.67 | TSHR (0.40) | TSHRALDH1A1THRBHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686149-B1 | USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES | OXIS ISLE OF MAN LTD (GB) | 2002-04-24 | — | — | EP | disclosed |
| EP-1041067-A2 | Use of 2-mercapto-imidazole derivatives substituted in position 4 ( or 5 ) as antioxidants | OXIS Isle of Man, Limited (GB) | 2000-10-04 | — | — | EP | disclosed |
| US-6056965-A | 2-mercapto-imidazole derivatives substituted in position 4 (or 5) as antioxidizing agents, method of preparation and applications in the pharmaceutical, cosmetic or food industries | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |