SCHEMBL753758

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751254	0.87	HPGD (0.50)	MMP3CNR2GPR55POLBTP53
	SCHEMBL751551	0.87	GAA (0.38)	MMP3POLBTP53LMNAALDH1A1
	SCHEMBL755706	0.86	MMP3 (0.41)	MMP3POLBTP53LMNAMMP12
	SCHEMBL755446	0.84	TEAD4 (0.42)	CNR2GPR55POLBUSP2ALDH1A1
	SCHEMBL751255	0.83	KMT2A (0.38)	MMP3CNR2GPR55POLBLMNA
	SCHEMBL753335	0.83	CNR2 (0.38)	MMP3CNR2GPR55POLBLMNA
	SCHEMBL16925489	0.83	FAAH (0.39)	CNR2POLBTP53LMNATHRB
	SCHEMBL755559	0.82	MMP3 (0.47)	MMP3CNR2GPR55POLBLMNA
	SCHEMBL755356	0.82	PTGER1 (0.39)	POLBTP53LMNAALDH1A1
	Dimethylamine SCHEMBL752802	0.81	CNR2 (0.38)	MMP3CNR2GPR55POLBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.