SCHEMBL755446

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753335	0.86	CNR2 (0.38)	ALDH1A1POLBCNR2GPR55KMT2A
	SCHEMBL753088	0.85	POLB (0.38)	ALDH1A1MAPTPOLBCNR2GPR55
	SCHEMBL755559	0.85	MMP3 (0.47)	ALDH1A1KDM4EGAAPOLBCNR2
	SCHEMBL753758	0.84	MMP3 (0.38)	ALDH1A1GAAPOLBCNR2GPR55
	Dimethylamine SCHEMBL752802	0.82	CNR2 (0.38)	ALDH1A1GAAMAPTPOLBCNR2
	SCHEMBL755450	0.82	POLB (0.36)	ALDH1A1POLBCNR2GPR55USP2
	Methylamine SCHEMBL753441	0.82	CNR2 (0.38)	ALDH1A1KDM4EMAPTPOLBCNR2
	SCHEMBL754276	0.82	ESR1 (0.35)	TEAD4ALDH1A1POLBCNR2GPR55
	SCHEMBL753407	0.81	HTT (0.49)	ALDH1A1KDM4EMAPTPOLBCNR2
	SCHEMBL755706	0.81	MMP3 (0.41)	ALDH1A1KDM4EPOLBL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.