Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.33 |
| ▸ | KDM5C | P41229 | 3/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18007131 | 0.88 | SLC22A6 (0.42) | LMNAOR51E2TSHRMEN1KMT2A | |
| SCHEMBL6380324 | 0.83 | STING1 (0.35) | HDAC3HDAC1HDAC2HDAC8TSHR | |
| SCHEMBL395187 | 0.81 | ALDH1A1 (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7085941 | 0.81 | ALOX15 (0.39) | EGLN1NAALAD2TET2TSHRDGAT1 | |
| SCHEMBL23161821 | 0.80 | TSHR (0.50) | LMNATET2KDM4ETSHRDGAT1 | |
| SCHEMBL9362827 | 0.79 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL9540623 | 0.79 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL28401903 | 0.79 | DGAT1 (0.30) | DGAT1GAA | |
| SCHEMBL13460765 | 0.78 | EGLN1 (0.41) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL8198264 | 0.78 | EGLN1 (0.44) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259292-B1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) | 2020-04-08 | — | — | EP | disclosed |
| US-10259907-B2 | Block copolymers with surface-active junction groups, compositions and processes thereof | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.À R.L. (LU) | 2019-04-16 | — | — | US | disclosed |
| EP-3259292-A1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ Electronic Materials Luxembourg S.à.r.l. (LU) | 2017-12-27 | — | — | EP | disclosed |
| WO-2017144385-A1 | BLOCK COPOLYMERS WITH LINEAR SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) | 2017-08-31 | — | — | WO | disclosed |
| WO-2016131900-A1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) | 2016-08-25 | — | — | WO | disclosed |
| US-20160244557-A1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S. a. r. l. (LU) | 2016-08-25 | — | — | US | disclosed |
| EP-1202717-A2 | NAALADASE INHIBITORS IN ANXIETY AND MEMORY DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1093453-A1 | NAALADASE INHIBITORS USEFUL AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS | GUILFORD PHARMACEUTICALS INC. (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2001001974-A2 | NAALADASE INHIBITORS IN ANXIETY AND MEMORY DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000001668-A2 | NAALADASE INHIBITORS USEFUL AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-01-13 | — | — | WO | disclosed |
| WO-1999033847-A9 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARM INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033847-A1 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | disclosed |