Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540147 | 0.79 | KMT2A (0.55) | ALDH1A1SMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL7534511 | 0.76 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GAAMAPTHTT | |
| SCHEMBL7539138 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2GAAMAPTHTT | |
| SCHEMBL7242715 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL15265867 | 0.72 | KMT2A (0.40) | ALDH1A1SMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL6067968 | 0.71 | NPC1 (0.54) | PGK1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL6068038 | 0.70 | LMNA (0.49) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL1842323 | 0.70 | NPC1 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL7535028 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MAPTKMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL1844041 | 0.69 | NPC1 (0.51) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1422262-A | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors | ABBOTT GMBH & CO KG (DE) | 2003-06-04 | — | — | CN | disclosed |
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |