SCHEMBL7537762

SCHEMBL7537762

CC(=O)NC(=O)c1cc(C=O)c2ccccc2c1C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PADI4 Q9UM07 1/20 0.38
MCL1 Q07820 2/20 0.37
POLB P06746 3/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 2/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
PLEC Q15149 1/20 0.33
ERN1 O75460 3/20 0.33
EPHX1 P07099 2/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
IMPDH2 P12268 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NSD2 O96028 1/20 0.31
PLK1 P53350 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7539682 0.85 POLB (0.47) PADI4MCL1POLBMEN1KMT2A
SCHEMBL7537763 0.80 PLK1 (0.40) MCL1POLBMEN1KMT2AMTNR1A
SCHEMBL7544092 0.79 ALDH1A1 (0.46) POLBMEN1KMT2AHTTMAPT
SCHEMBL7542230 0.77 MCL1 (0.40) PADI4MCL1POLBMEN1KMT2A
SCHEMBL7536525 0.76 PADI4 (0.43) PADI4MCL1MEN1KMT2AHTT
SCHEMBL7543583 0.75 NPC1 (0.53) POLBMEN1KMT2AMAPTTSHR
SCHEMBL10384781 0.69 ALDH1A1 (0.48) PADI4MCL1MEN1KMT2AMAPT
SCHEMBL7537768 0.67 KDM4E (0.36) POLBMEN1KMT2AHTTMTNR1A
SCHEMBL8505311 0.66 PLK1 (0.68) POLBMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL9978633 0.66 MCL1 (0.59) MCL1POLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 PADI4 4800/4885MCL1 3029/4885POLB 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.