Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012346 | 0.80 | HSD11B1 (0.43) | LMNAALDH1A1L3MBTL1CCR1NPSR1 | |
| SCHEMBL8011596 | 0.79 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1LMNAGRM1 | |
| SCHEMBL4681264 | 0.79 | L3MBTL1 (0.51) | RAB9ASMN1; SMN2NPC1NPBWR1MCHR1 | |
| SCHEMBL4678369 | 0.76 | NPC1 (0.39) | RAB9ASMN1; SMN2NPC1NPBWR1MCHR1 | |
| SCHEMBL7600596 | 0.75 | GAA (0.37) | RAB9ANPC1KMT2APAX8L3MBTL1 | |
| SCHEMBL7017303 | 0.74 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1LMNANPBWR1 | |
| SCHEMBL4678854 | 0.74 | HTT (0.46) | RAB9ASMN1; SMN2NPC1NPBWR1MCHR1 | |
| SCHEMBL7092396 | 0.74 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1LMNANPBWR1 | |
| SCHEMBL7093369 | 0.73 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1LMNANPBWR1 | |
| SCHEMBL4679289 | 0.73 | TRPC1 (0.39) | RAB9ANPC1LMNANPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1262536-C | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2006-07-05 | — | — | CN | disclosed |
| EP-0934254-B1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6333413-B1 | PYRIDAZIN-3-ONE DERIVATIVES BY CYCLIZING THE CARBOXY-SUBSTITUTED HYDRAZONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-25 | — | — | US | disclosed |
| US-6156891-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| US-6093818-A | Substituted pyridazin-3-one compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-07-25 | — | — | US | disclosed |
| CN-1241175-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2000-01-12 | — | — | CN | disclosed |
| EP-0943610-A1 | Substituted Pyridazin-3-one compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0934254-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017632-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-30 | — | — | WO | disclosed |