Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.68 |
| ▸ | MMP3 | P08254 | 8/20 | 0.68 |
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | MMP14 | P50281 | 2/20 | 0.68 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436523 | 1.00 | MMP2 (0.68) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6433752 | 0.94 | MMP2 (0.66) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7432313 | 0.94 | MMP2 (0.66) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6971949 | 0.93 | MMP2 (0.68) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6971954 | 0.93 | MMP2 (0.68) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6956464 | 0.92 | MMP3 (0.81) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7408826 | 0.89 | MMP2 (0.82) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587437 | 0.87 | MMP2 (0.83) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6590361 | 0.85 | MMP3 (0.60) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6437467 | 0.82 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-A1 | METALLOPROTEASE INHIBITORS | Pfizer Limited (GB) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000074681-A1 | METALLOPROTEASE INHIBITORS | PFIZER LIMITED (GB) | 2000-12-14 | — | — | WO | disclosed |