SCHEMBL753812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL765086	0.87	NPC1 (0.47)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL753818	0.84	HPGD (0.47)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL12266074	0.81	NPC1 (0.46)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL14046413	0.74	NPC1 (0.44)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL13218214	0.74	TP53 (0.42)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL4280987	0.73	NPC1 (0.41)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL825685	0.73	NR1I3 (0.46)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL13255448	0.73	NPC1 (0.40)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL823357	0.72	GABRA1 (0.41)	NPC1RAB9AHPGDSMN1; SMN2TP53
	SCHEMBL13255477	0.71	NPC1 (0.48)	NPC1RAB9AHPGDSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.