Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753812 | 0.87 | NPC1 (0.46) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL753818 | 0.85 | HPGD (0.47) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL12266074 | 0.73 | NPC1 (0.46) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL11948563 | 0.70 | NPC1 (0.41) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL13255414 | 0.70 | NPC1 (0.48) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL13255448 | 0.69 | NPC1 (0.40) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL823357 | 0.68 | GABRA1 (0.41) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL13237374 | 0.68 | NPC1 (0.54) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL14046413 | 0.68 | NPC1 (0.44) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL13255439 | 0.68 | HPGD (0.44) | NPC1RAB9AHPGDSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |