Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.51 |
| ▸ | CASP3 | P42574 | 6/20 | 0.51 |
| ▸ | CASP7 | P55210 | 6/20 | 0.51 |
| ▸ | CASP6 | P55212 | 6/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532390 | 0.90 | CASP1 (0.49) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6661977 | 0.83 | CASP1 (0.47) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6479150 | 0.79 | CASP1 (0.52) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6478370 | 0.78 | KMT2A (0.47) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6472835 | 0.77 | CASP1 (0.51) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6474104 | 0.77 | KMT2A (0.45) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6474177 | 0.75 | CASP1 (0.49) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6478978 | 0.74 | CASP1 (0.48) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6472884 | 0.73 | KMT2A (0.43) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6474262 | 0.71 | KMT2A (0.51) | KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | claimed |