SCHEMBL753864

SCHEMBL753864

O=S(=O)(C(Br)(Br)Cc1ccccc1Br)C(Br)(Br)Cc1ccccc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
IDO1 P14902 2/20 0.41
PLCG1 P19174 1/20 0.41
CA1 P00915 6/20 0.40
CA2 P00918 6/20 0.40
CA9 Q16790 5/20 0.40
CA12 O43570 4/20 0.40
HPGD P15428 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
RIPK1 Q13546 1/20 0.37
CA5A P35218 1/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPK1 P28482 1/20 0.36
THPO P40225 1/20 0.36
TSHR P16473 1/20 0.35
CYP2A13 Q16696 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753729 0.78 ALDH1A1 (0.46) TAAR1IDO1HPGDTSHRALDH1A1
SCHEMBL753876 0.78 MEN1 (0.41) TAAR1CA2HPGDLMNATSHR
SCHEMBL1691374 0.71 RIPK1 (0.47) TAAR1IDO1RIPK1LMNACYP2D6
SCHEMBL263115 0.71 TAAR1 (0.46) TAAR1IDO1CA1CA2CA9
SCHEMBL5661830 0.71 TAAR1 (0.46) TAAR1IDO1PLCG1CA1CA2
SCHEMBL2396949 0.68 TAAR1 (0.44) TAAR1IDO1PLCG1CA1CA2
SCHEMBL271620 0.68 HPGD (0.44) TAAR1IDO1PLCG1CA1CA2
SCHEMBL15638695 0.68 TAAR1 (0.50) TAAR1IDO1CA1CA2CA4
SCHEMBL10654193 0.68 TAAR1 (0.43) TAAR1IDO1PLCG1CA1CA2
SCHEMBL2401345 0.68 RIPK1 (0.45) TAAR1IDO1RIPK1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed