SCHEMBL7538656

SCHEMBL7538656

OCc1ccc(OC2CCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
TSHR P16473 1/20 0.63
ALOX12 P18054 1/20 0.54
PARP10 Q53GL7 1/20 0.49
FAAH O00519 1/20 0.45
EPHX2 P34913 1/20 0.45
ACACB O00763 3/20 0.45
HRH1 P35367 1/20 0.45
GRM2 Q14416 1/20 0.44
LTA4H P09960 1/20 0.44
NAAA Q02083 1/20 0.44
FFAR1 O14842 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
FURIN P09958 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671079 0.98 ALDH1A1 (0.61) ALDH1A1TSHRALOX12PARP10FAAH
SCHEMBL4661973 0.96 ALDH1A1 (0.58) ALDH1A1TSHRALOX12PARP10FAAH
SCHEMBL12489770 0.92 ALDH1A1 (0.53) ALDH1A1TSHRALOX12PARP10FAAH
SCHEMBL16902893 0.92 ALDH1A1 (0.53) ALDH1A1TSHRALOX12PARP10FAAH
SCHEMBL16902888 0.89 FURIN (0.56) ALDH1A1TSHRALOX12PARP10FAAH
SCHEMBL16902873 0.84 ALDH1A1 (0.46) ALDH1A1TSHRALOX12FAAHEPHX2
SCHEMBL19050238 0.83 HRH1 (0.66) ALDH1A1TSHRALOX12FAAHEPHX2
SCHEMBL2166449 0.80 ALDH1A1 (0.55) ALDH1A1TSHRALOX12PARP10ACACB
SCHEMBL2242868 0.80 PARP10 (0.55) ALDH1A1TSHRALOX12PARP10EPHX2
SCHEMBL16702147 0.80 HRH3 (0.57) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1854128-A Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds MASSACHUSETTS INST TECHNOLOGY (US) 2006-11-01 CN disclosed
CN-1266112-C Copper-catalyzed carbon-heteroatom and carbon-carbon bond formation MASSACHUSETTS INST TECHNOLOGY (US) 2006-07-26 CN disclosed
EP-0711760-B1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2002-05-15 EP disclosed
EP-0882720-B1 METHODS FOR MODIFYING 1,3,5-TRIAZINE DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2001-08-22 EP disclosed
US-6130332-A USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-10 US disclosed
US-6127538-A HYDROXYALKYLATION OF A TRIAMINO TRIAZINE DERIVATIVE HAVING AT LEAST ONE REACTIVE NITROGEN BY REACTING WHILE HEATING WITH AN ALKANEDIOL OR ITS ADDUCT IN THE PRESENCE OF HYDROGEN AND A METAL CATALYST; BY-PRODUCT INHIBITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-03 US disclosed
EP-0882720-A1 METHODS FOR MODIFYING 1,3,5-TRIAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-12-09 EP disclosed
US-5792867-A Method of alkylating of triazine derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
EP-0760369-A1 PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-05 EP disclosed
EP-0711760-A1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-05-15 EP disclosed