SCHEMBL16702147

SCHEMBL16702147

OCc1ccc(OC2CCN(C3CCC3)CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.57
KCNH2 Q12809 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2819889 0.88 HRH3 (0.55) HRH3
SCHEMBL2821556 0.85 HRH3 (0.57) HRH3KCNH2
SCHEMBL12484261 0.85 HRH3 (0.57) HRH3KCNH2
SCHEMBL2821339 0.85 HRH3 (0.52) HRH3
SCHEMBL4661973 0.84 ALDH1A1 (0.58) HRH3
SCHEMBL3272606 0.83 HRH3 (0.57) HRH3
SCHEMBL737639 0.81 HRH3 (0.63) HRH3KCNH2
SCHEMBL4221612 0.80 HRH3 (0.52) HRH3KCNH2
SCHEMBL7538656 0.80 ALDH1A1 (0.63) HRH3
SCHEMBL16902893 0.80 ALDH1A1 (0.53) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015069110-A1 MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS AAPA B.V. (NL) 2015-05-14 WO disclosed