Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.55 |
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | CPA1 | P15085 | 4/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538685 | 1.00 | ACE (0.55) | ACEMMECPA1ACE2PSMB5 | |
| SCHEMBL7544847 | 0.92 | IL1RN (0.53) | ACEMMECPA1ACE2PSMB5 | |
| SCHEMBL7544851 | 0.92 | IL1RN (0.53) | ACEMMECPA1ACE2PSMB5 | |
| SCHEMBL7540879 | 0.85 | MME (0.55) | ACEMMECPA1ACE2PPARG | |
| SCHEMBL7540882 | 0.85 | MME (0.55) | ACEMMECPA1ACE2PPARG | |
| SCHEMBL7539136 | 0.81 | GPR34 (0.50) | ACEMMECPA1ACE2PSMB5 | |
| SCHEMBL7539133 | 0.81 | GPR34 (0.50) | ACEMMECPA1ACE2PSMB5 | |
| SCHEMBL7541085 | 0.77 | ALDH1A1 (0.53) | ACEMMECPA1ACE2PPARG | |
| SCHEMBL7541086 | 0.77 | ALDH1A1 (0.53) | ACEMMECPA1ACE2PPARG | |
| SCHEMBL8210636 | 0.76 | ACE (0.64) | ACEMMECPA1ACE2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |