Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 2/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544851 | 1.00 | IL1RN (0.53) | IL1RNERAP2ERAP1ALDH1A1MEN1 | |
| SCHEMBL7538677 | 0.92 | ACE (0.55) | PPARGPSMB5MMEACECPA1 | |
| SCHEMBL7538685 | 0.92 | ACE (0.55) | PPARGPSMB5MMEACECPA1 | |
| SCHEMBL7541086 | 0.85 | ALDH1A1 (0.53) | IL1RNERAP2ERAP1ALDH1A1MEN1 | |
| SCHEMBL7541085 | 0.85 | ALDH1A1 (0.53) | IL1RNERAP2ERAP1ALDH1A1MEN1 | |
| SCHEMBL7541807 | 0.81 | IL1RN (0.49) | IL1RNERAP2ERAP1ALDH1A1PPARG | |
| SCHEMBL7541803 | 0.81 | IL1RN (0.49) | IL1RNERAP2ERAP1ALDH1A1PPARG | |
| SCHEMBL8415923 | 0.77 | REN (0.65) | IL1RNERAP2ERAP1PPARGCAPN1 | |
| SCHEMBL7540882 | 0.77 | MME (0.55) | PPARGMMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL8414461 | 0.77 | ERAP2 (0.66) | IL1RNERAP2ERAP1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |