Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 7/20 | 0.56 |
| ▸ | ACE | P12821 | 11/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547257 | 0.93 | FOLH1 (0.55) | FOLH1MMEACENAALAD2CPA1 | |
| SCHEMBL7538620 | 0.86 | FOLH1 (0.45) | FOLH1MMEACENAALAD2CPA1 | |
| SCHEMBL7547273 | 0.86 | FOLH1 (0.45) | FOLH1MMEACENAALAD2CPA1 | |
| SCHEMBL7547266 | 0.86 | FOLH1 (0.45) | FOLH1MMEACENAALAD2CPA1 | |
| SCHEMBL7538785 | 0.85 | FOLH1 (0.54) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7541870 | 0.85 | FOLH1 (0.54) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7546158 | 0.84 | FOLH1 (0.53) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7540008 | 0.84 | MMP3 (0.50) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7547307 | 0.84 | FOLH1 (0.52) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7541769 | 0.82 | HDAC1 (0.51) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |