Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 8/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538785 | 0.93 | FOLH1 (0.54) | FOLH1ACEMMEMAPTCPA1 | |
| SCHEMBL7541870 | 0.93 | FOLH1 (0.54) | FOLH1ACEMMEMAPTCPA1 | |
| SCHEMBL7538694 | 0.93 | FOLH1 (0.59) | FOLH1ACEMMENAALAD2CPA1 | |
| SCHEMBL7546158 | 0.92 | FOLH1 (0.53) | FOLH1ACEMMEMAPTCPA1 | |
| SCHEMBL7547307 | 0.91 | FOLH1 (0.52) | FOLH1ACEMMEMAPTCPA1 | |
| SCHEMBL7544917 | 0.90 | FPR2 (0.56) | FOLH1MMP3MMP2 | |
| SCHEMBL7545943 | 0.88 | FOLH1 (0.48) | FOLH1ACEMMEMAPTCPA1 | |
| SCHEMBL7538620 | 0.88 | FOLH1 (0.45) | FOLH1ACEMMENAALAD2MAPT | |
| SCHEMBL7547266 | 0.87 | FOLH1 (0.45) | FOLH1ACEMMENAALAD2MAPT | |
| SCHEMBL7547273 | 0.87 | FOLH1 (0.45) | FOLH1ACEMMENAALAD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |