Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541870 | 0.92 | FOLH1 (0.54) | FOLH1MAPTMMP3MMP2MME | |
| SCHEMBL7538785 | 0.92 | FOLH1 (0.54) | FOLH1MAPTMMP3MMP2MME | |
| SCHEMBL7546158 | 0.91 | FOLH1 (0.53) | FOLH1MAPTMMP3FFAR1MMP2 | |
| SCHEMBL7547257 | 0.91 | FOLH1 (0.55) | FOLH1MAPTMMP3MMP2MME | |
| SCHEMBL7544917 | 0.89 | FPR2 (0.56) | FOLH1HDAC1HDAC6MMP3FFAR1 | |
| SCHEMBL7547253 | 0.88 | MME (0.42) | FOLH1MAPTALDH1A1LMNAMMP3 | |
| SCHEMBL7545943 | 0.87 | FOLH1 (0.48) | FOLH1MAPTMMP3MMP2MME | |
| SCHEMBL7543339 | 0.87 | MAPT (0.40) | FOLH1MAPTALDH1A1LMNAMMP3 | |
| SCHEMBL7543337 | 0.87 | MAPT (0.40) | FOLH1MAPTALDH1A1LMNAMMP3 | |
| SCHEMBL7540008 | 0.85 | MMP3 (0.50) | FOLH1MMP3MMP2MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |