SCHEMBL7538697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8959237	0.87	CASP6 (0.50)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL7195634	0.82	NR4A1 (0.49)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL27677443	0.81	NQO2 (0.50)	NQO2CYP1A2CYP2C9TSHRPTPRA
	SCHEMBL7188643	0.80	ESR1 (0.56)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL6571754	0.80	CASP6 (0.51)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL27677444	0.80	NQO2 (0.48)	NQO2CYP1A2CYP2C9TSHRPTPRA
	SCHEMBL3933078	0.79	METAP2 (0.59)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL10878438	0.79	MEN1 (0.49)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL29077017	0.78	METAP2 (0.58)	KMT2AMEN1GAAESR1ESR2
	SCHEMBL8837674	0.78	MEN1 (0.50)	KMT2AMEN1GAAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.