Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537394 | 0.93 | SLC10A2 (0.53) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7534376 | 0.92 | L3MBTL1 (0.52) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7538739 | 0.89 | MEN1 (0.49) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7534822 | 0.88 | HTT (0.51) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7533623 | 0.88 | ACLY (0.55) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7531893 | 0.88 | HTT (0.50) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7532675 | 0.87 | ACLY (0.52) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7538051 | 0.87 | HTT (0.49) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7531361 | 0.86 | L3MBTL1 (0.53) | ACLYHTTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7531845 | 0.86 | HTT (0.47) | ACLYHTTL3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |