SCHEMBL753885

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16892973	1.00	CYP1A2 (0.47)	CYP1A2CYP2C9HIF1ARAB9APOLB
	SCHEMBL12824208	0.84	RAB9A (0.46)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL847229	0.83	CYP1A2 (0.50)	CYP1A2CYP2C9HIF1ARAB9APOLB
	SCHEMBL304022	0.82	MGAM (0.50)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL890158	0.82	KDM4E (0.49)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL305325	0.82	MGAM (0.50)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL305326	0.82	MGAM (0.50)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL2631568	0.82	CYP1A2 (0.49)	CYP1A2CYP2C9HIF1ARAB9APOLB
	SCHEMBL13748064	0.81	KDM4E (0.48)	CYP1A2RAB9APOLBLMNATSHR
	SCHEMBL888730	0.80	KDM4E (0.47)	CYP1A2RAB9APOLBLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.