Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544830 | 0.96 | MMP3 (0.47) | ITGB1ITGA4MMP2MMP3REN | |
| SCHEMBL7542034 | 0.93 | ITGB1 (0.47) | ITGB1ITGA4MMP2MMP3REN | |
| SCHEMBL7540009 | 0.92 | ITGB1 (0.45) | ITGB1ITGA4MMP2MMP3REN | |
| SCHEMBL7546973 | 0.92 | ANPEP (0.52) | ITGB1ITGA4MMP3RENMMP1 | |
| SCHEMBL7541665 | 0.89 | MEN1 (0.46) | ITGB1ITGA4MMP2MMP3REN | |
| SCHEMBL7540085 | 0.89 | CTSL (0.42) | FOLH1ACEOPRM1OPRD1MMP2 | |
| SCHEMBL7547312 | 0.89 | MMP3 (0.44) | ITGB1ITGA4MMP2MMP3REN | |
| SCHEMBL7547334 | 0.89 | NPY4R (0.45) | FOLH1ITGB1ITGA4NPY1RNPY2R | |
| SCHEMBL7540592 | 0.88 | ACE (0.39) | FOLH1ITGB1ITGA4ACEOPRM1 | |
| SCHEMBL7540598 | 0.88 | ACE (0.39) | FOLH1ITGB1ITGA4ACEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |