Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 7/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544830 | 0.93 | MMP3 (0.47) | MMP3MMP2MMP1RENGAA | |
| SCHEMBL7541440 | 0.90 | MMP3 (0.45) | MMP3MMP2MMP1GAAMAPT | |
| SCHEMBL7541198 | 0.90 | CTSL (0.43) | MMP3MMP2MMP1RENGAA | |
| SCHEMBL7540944 | 0.90 | MMP3 (0.42) | MMP3MMP2MMP1RENGAA | |
| SCHEMBL7541215 | 0.90 | ITGB1 (0.42) | MMP3MMP2MMP1RENGAA | |
| SCHEMBL7541217 | 0.90 | ITGB1 (0.42) | MMP3MMP2MMP1RENGAA | |
| SCHEMBL7539004 | 0.89 | FOLH1 (0.46) | MMP3MMP2MMP1RENMMP9 | |
| SCHEMBL7542034 | 0.89 | ITGB1 (0.47) | MMP3MMP2MMP1RENMMP9 | |
| SCHEMBL7540009 | 0.88 | ITGB1 (0.45) | MMP3MMP2MMP1RENITGB1 | |
| SCHEMBL7540132 | 0.87 | ITGB1 (0.43) | MMP3MMP2MMP1RENGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |