Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MYOC | Q99972 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567387 | 0.91 | CTSS (0.34) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7539259 | 0.91 | CTSS (0.34) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7541908 | 0.90 | MEN1 (0.44) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7539416 | 0.90 | GAA (0.40) | MAPTMAPK1ALDH1A1GAARAB9A | |
| SCHEMBL7545845 | 0.90 | MAPK1 (0.37) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7541454 | 0.90 | FOLH1 (0.38) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7539003 | 0.89 | MAPK1 (0.38) | MAPK1LMNAALDH1A1FPR2 | |
| SCHEMBL7539173 | 0.88 | ANPEP (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7539323 | 0.88 | MEN1 (0.39) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL7538130 | 0.87 | MEN1 (0.41) | MEN1KMT2AMAPTNPSR1MYOC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |