Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539416 | 0.94 | GAA (0.40) | FPR2ANPEPALDH1A1MAPTREN | |
| SCHEMBL7545845 | 0.93 | MAPK1 (0.37) | FPR2ANPEPALDH1A1LMNAMAPT | |
| SCHEMBL7539003 | 0.92 | MAPK1 (0.38) | FOLH1FPR2ANPEPALDH1A1LMNA | |
| SCHEMBL7539173 | 0.92 | ANPEP (0.46) | FPR2ANPEPRAB9ASMN1; SMN2 | |
| SCHEMBL7567053 | 0.90 | CTSK (0.36) | FOLH1MAPTRENGAAHPGD | |
| SCHEMBL7538431 | 0.90 | CTSK (0.36) | FOLH1MAPTRENGAAHPGD | |
| SCHEMBL7539437 | 0.90 | MEN1 (0.41) | FPR2ALDH1A1LMNAMAPTGAA | |
| SCHEMBL7542028 | 0.89 | FOLH1 (0.42) | FOLH1FPR2ANPEPALDH1A1LMNA | |
| SCHEMBL7547322 | 0.87 | GAA (0.42) | ALDH1A1MAPTRENGAAHPGD | |
| SCHEMBL7541860 | 0.85 | FOLH1 (0.39) | FOLH1FPR2ANPEPALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |