Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539416 | 0.94 | GAA (0.40) | MAPK1FPR2ALDH1A1PYGLCYP2C9 | |
| SCHEMBL7541454 | 0.93 | FOLH1 (0.38) | MAPK1FPR2ALDH1A1PYGLCYP2C9 | |
| SCHEMBL7539003 | 0.92 | MAPK1 (0.38) | MAPK1FPR2ALDH1A1MAPK14ANPEP | |
| SCHEMBL7539173 | 0.92 | ANPEP (0.46) | FPR2SMN1; SMN2ANPEP | |
| SCHEMBL7541260 | 0.90 | CTSK (0.36) | MAPK1ALDH1A1PYGLCYP2C9SMN1; SMN2 | |
| SCHEMBL7566320 | 0.90 | CTSK (0.36) | MAPK1ALDH1A1PYGLCYP2C9SMN1; SMN2 | |
| SCHEMBL7539437 | 0.90 | MEN1 (0.41) | MAPK1FPR2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7542294 | 0.89 | MAPK1 (0.41) | MAPK1FPR2ALDH1A1IDO1MAPK14 | |
| SCHEMBL7547322 | 0.87 | GAA (0.42) | ALDH1A1CYP2C9SMN1; SMN2MAPT | |
| SCHEMBL7540799 | 0.87 | ITGB1 (0.42) | MAPK1FPR2ALDH1A1ANPEPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |