Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163932 | 0.83 | ADRB2 (0.60) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL17177747 | 0.81 | RAB9A (0.58) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL1993827 | 0.80 | ALDH1A1 (0.69) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL7773822 | 0.80 | RAB9A (0.61) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL23484189 | 0.80 | ADRB2 (0.56) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL12019106 | 0.79 | ADRB2 (0.59) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL7537991 | 0.78 | RAB9A (0.55) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL11020137 | 0.77 | TDP1 (0.63) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL29890037 | 0.77 | CA12 (0.67) | RAB9ANPC1ESR1ESR2CA12 | |
| SCHEMBL149288 | 0.77 | CA12 (0.67) | RAB9ANPC1ESR1ESR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| EP-0790991-B1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX INC (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5773628-A | CHEMILUMINESCENT ASSAY OF PHOSPHATASE | TROPIX, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0790991-A4 | — | — | 1997-09-03 | — | — | EP | disclosed |
| EP-0790991-A1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015122-A1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX, INC. (US) | 1996-05-23 | — | — | WO | disclosed |