Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287949 | 0.86 | HTT (0.36) | SMN1; SMN2KMT2A | |
| SCHEMBL7540000 | 0.81 | TK1 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7534620 | 0.80 | UPP1 (0.35) | ALDH1A1MEN1POLBKMT2ATDP1 | |
| SCHEMBL7541259 | 0.78 | DUT (0.54) | — | |
| SCHEMBL13384443 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL13384426 | 0.71 | UPP1 (0.39) | KMT2A | |
| SCHEMBL9016400 | 0.71 | UPP1 (0.53) | — | |
| SCHEMBL20870268 | 0.70 | GRIA1 (0.38) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL12341287 | 0.70 | HTT (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL7213480 | 0.69 | PKM (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG IND LTD (KR) | 2002-05-08 | — | — | EP | disclosed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |