Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7578658 | 0.83 | HPGD (0.36) | PTPN1PTPN2 | |
| SCHEMBL7536578 | 0.77 | PTPN1 (0.38) | PTPN1PTPRCPTPN2 | |
| SCHEMBL7512126 | 0.76 | PTPN1 (0.53) | PTPN1PTPRCPTPN2 | |
| SCHEMBL7693899 | 0.73 | PTPN1 (0.53) | PTPN1PTPRCPTPN2 | |
| SCHEMBL7562771 | 0.72 | PTPN1 (0.35) | PTPN1PTPRCPTPN2 | |
| SCHEMBL7557647 | 0.72 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL6394168 | 0.71 | PTPN1 (0.36) | PTPN1PTPN2 | |
| SCHEMBL7854135 | 0.71 | PTPN1 (0.58) | PTPN1PTPRCPTPN2 | |
| SCHEMBL27558196 | 0.70 | PTPN1 (0.43) | PTPN1PTPRCPTPN2 | |
| SCHEMBL7095258 | 0.70 | POLB (0.45) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214060-A2 | METHOD OF INHIBITING PROTEIN TYROSINE PHOSPHATASE 1B AND/OR T-CELL PROTEIN TYROSINE PHOSPHATASE AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001017516-A2 | METHOD OF INHIBITING PROTEIN TYROSINE PHOSPHATASE 1B AND/OR T-CELL PROTEIN TYROSINE PHOSPHATASE AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 | NOVO NORDISK A/S (DK) | 2001-03-15 | — | — | WO | disclosed |