Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095255 | 1.00 | POLB (0.45) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL5768826 | 0.84 | PTPN1 (0.50) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL7578658 | 0.74 | HPGD (0.36) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL7557647 | 0.73 | PTPN1 (0.37) | KMT2AMEN1GAAALDH1A1HPGD | |
| SCHEMBL5810842 | 0.71 | RAB9A (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7096725 | 0.71 | PTPN1 (0.58) | KMT2AALDH1A1HPGDHSD17B10PTPN1 | |
| SCHEMBL7096724 | 0.71 | PTPN1 (0.58) | KMT2AALDH1A1HPGDHSD17B10PTPN1 | |
| SCHEMBL5810837 | 0.71 | RAB9A (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7537220 | 0.71 | PTPN1 (0.37) | KMT2AMEN1SMN1; SMN2PTPN1HTT | |
| SCHEMBL5794533 | 0.71 | PTPN1 (0.40) | POLBKMT2AMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301516-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |