Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543257 | 0.81 | HTR2C (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL10850914 | 0.76 | HTR2C (0.45) | TRPM5HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL3028639 | 0.76 | TRPM5 (0.41) | TRPM5HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL10292643 | 0.75 | FYN (0.40) | — | |
| SCHEMBL6985110 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL2501307 | 0.72 | CHRNB2 (0.42) | HTR2ACHRNB2CHRNA4 | |
| SCHEMBL6981317 | 0.71 | HTR1A (0.50) | — | |
| SCHEMBL13428611 | 0.71 | CYP3A4 (0.43) | — | |
| SCHEMBL333286 | 0.71 | CYP3A4 (0.43) | — | |
| SCHEMBL7431595 | 0.71 | CYP3A4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940386-B1 | Benzocyclobutan compounds, their process for preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-05-22 | — | — | EP | disclosed |
| US-6107345-A | ANTIDEPRESSANT; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-08-22 | — | — | US | disclosed |
| EP-0940386-A1 | Benzocyclobutan compounds, their process for preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-09-08 | — | — | EP | disclosed |