Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584556 | 0.83 | KCNH2 (0.41) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL6581298 | 0.81 | KCNH2 (0.42) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL6579248 | 0.80 | KCNH2 (0.42) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL6583582 | 0.75 | KCNH2 (0.70) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL6583579 | 0.75 | KCNH2 (0.70) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL2887116 | 0.74 | ALDH1A1 (0.38) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL2882585 | 0.74 | ALDH1A1 (0.38) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL2883779 | 0.74 | ALDH1A1 (0.38) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL3947551 | 0.74 | ALDH1A1 (0.38) | KCNH2ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL2882586 | 0.74 | ALDH1A1 (0.38) | KCNH2ALDH1A1KMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |