Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581298 | 0.89 | KCNH2 (0.42) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6579248 | 0.88 | KCNH2 (0.42) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7540170 | 0.83 | KCNH2 (0.40) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6584554 | 0.77 | KCNH2 (0.69) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6584563 | 0.77 | KCNH2 (0.69) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6584560 | 0.77 | KCNH2 (0.69) | KCNH2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7465262 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL11552606 | 0.71 | MEN1 (0.52) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7909935 | 0.71 | MEN1 (0.52) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL8933428 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214307-B1 | 4-OXYBENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6555574-B1 | Antiarrhythmic agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-29 | — | — | US | disclosed |