Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581298 | 0.93 | KCNH2 (0.42) | KCNH2ALDH1A1LMNAKEAP1NFE2L2 | |
| SCHEMBL6584556 | 0.88 | KCNH2 (0.41) | KCNH2ALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL7540170 | 0.80 | KCNH2 (0.40) | KCNH2ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL6579244 | 0.80 | KCNH2 (0.67) | KCNH2ALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL6579255 | 0.80 | KCNH2 (0.67) | KCNH2ALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL6579258 | 0.80 | KCNH2 (0.67) | KCNH2ALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL6893102 | 0.79 | KCNH2 (0.48) | KCNH2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6893115 | 0.79 | KCNH2 (0.48) | KCNH2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6893109 | 0.79 | KCNH2 (0.48) | KCNH2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7465260 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAKEAP1NFE2L2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214307-B1 | 4-OXYBENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6555574-B1 | Antiarrhythmic agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-29 | — | — | US | disclosed |