Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 13/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478872 | 0.89 | SLC7A5 (0.41) | ALDH1A1MAPTPTGS1DPP4SLC7A5 | |
| SCHEMBL26958374 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1DPP4SLC7A5 | |
| SCHEMBL500460 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| SCHEMBL500459 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| SCHEMBL16665454 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MAPTPTGS1DPP4SLC7A5 | |
| SCHEMBL20879474 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL1705950 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| SCHEMBL595786 | 0.79 | DGAT1 (0.39) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| SCHEMBL595785 | 0.79 | DGAT1 (0.39) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL737492 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1MAPTPTGS1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876336-B1 | AZAHEXANE DERIVATIVES AS SUBSTRATE ISOSTERS OF RETROVIRAL ASPARATE PROTEASES | NOVARTIS AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| US-6225345-B1 | FOR THERAPY OF ACQUIRED IMMUNODEFICIENCY SYNDROME | NOVARTIS AG (CH) | 2001-05-01 | — | — | US | disclosed |