Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.76 |
| ▸ | BCR | P11274 | 4/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.69 |
| ▸ | ESR1 | P03372 | 8/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899843 | 0.94 | ABL1 (0.69) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL14473526 | 0.88 | ESR2 (0.69) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL28147639 | 0.87 | HSD17B1 (0.68) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL31554258 | 0.83 | ABL1 (0.62) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL3020390 | 0.83 | HSD17B1 (0.76) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL547847 | 0.83 | ABL1 (0.62) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL28104773 | 0.83 | HSD17B1 (0.63) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL29869048 | 0.83 | ABL1 (0.62) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL1341494 | 0.83 | ESR2 (1.00) | ABL1ABCB1BCRESR2ESR1 | |
| SCHEMBL2699234 | 0.83 | ESR1 (1.00) | ABL1ABCB1BCRESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410754-B1 | OPTIC LENSES (GLASSES, SUNGLASSES); HIGH COLORABILITY AND SENSITIVITY TO ACTIVATING IRRADIATION | FLAMEL TECHNOLOGIES (FR) | 2002-06-25 | — | — | US | disclosed |
| US-20020049341-A1 | PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | FLAMEL TECHNOLOGIES (FR) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049341-A1 | PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | ALDH1A2, RB1, CRYAA | ABL1 4767/4885ABCB1 1225/4885BCR 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.