Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.49 |
| ▸ | CASP6 | P55212 | 17/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535127 | 0.90 | CASP3 (0.47) | CASP3CASP6CASP8 | |
| SCHEMBL7538962 | 0.89 | CASP3 (0.58) | CASP3CASP6CASP8 | |
| SCHEMBL8606968 | 0.86 | CASP3 (0.41) | CASP3CASP6CASP8 | |
| SCHEMBL7535627 | 0.84 | CASP3 (0.40) | CASP3CASP6CASP8 | |
| SCHEMBL7543444 | 0.81 | CASP3 (0.49) | CASP3CASP6CASP8 | |
| SCHEMBL8608833 | 0.77 | CASP3 (0.44) | CASP3CASP6CASP8 | |
| SCHEMBL7536449 | 0.76 | MMP2 (0.36) | CASP3CASP6CASP8 | |
| SCHEMBL27583485 | 0.76 | CASP3 (0.53) | CASP3CASP6CASP8 | |
| SCHEMBL7201348 | 0.76 | CASP3 (0.53) | CASP3CASP6CASP8 | |
| SCHEMBL5970017 | 0.75 | CASP3 (0.42) | CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159291-A1 | C-TERMINAL MODIFIED (N-SUBSTITUTED)-2-INDOLYLCARBONYLDIPEPTIDES AS INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals, Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001000658-A1 | C-TERMINAL MODIFIED (N-SUBSTITUTED)-2-INDOLYLCARBONYLDIPEPTIDES AS INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2001-01-04 | — | — | WO | disclosed |