SCHEMBL7540472

SCHEMBL7540472

Cc1cnc(OC(=O)O)c(O)n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
JAK3 P52333 1/20 0.30
CDC7 O00311 1/20 0.30
DBF4 Q9UBU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7537199 0.78 NAPRT (0.32) MEN1KMT2A
SCHEMBL7540465 0.71 KMT2A (0.37) MEN1KMT2ATDP1JAK3
SCHEMBL7534857 0.70 NAPRT (0.34)
SCHEMBL7156845 0.68
SCHEMBL15121730 0.68 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL2922727 0.68 HSD17B10 (0.31)
SCHEMBL22256869 0.68 SLCO1B1 (0.44) MEN1KMT2A
SCHEMBL24069013 0.67 ALDH1A1 (0.37) MEN1KMT2ATDP1JAK3
SCHEMBL4202441 0.67 KMT2A (0.41) MEN1KMT2ATDP1
SCHEMBL13242156 0.67 NPSR1 (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002029021-A2 BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE LONZA AG (CH) 2002-04-11 WO disclosed