SCHEMBL7534857

SCHEMBL7534857

O=C(O)Oc1nccnc1O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.34
KDM4E B2RXH2 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377060 0.85 NAPRT (0.36) NAPRTKDM4EHCAR2
SCHEMBL28007567 0.80 LMNA (0.34) KDM4E
SCHEMBL2636627 0.77 KDM4E (0.34) KDM4E
SCHEMBL3426359 0.76 NAPRT (0.39) NAPRTKDM4EHCAR2
SCHEMBL18398770 0.76 LMNA (0.39) NAPRTKDM4EHCAR2
SCHEMBL2304200 0.72 FTO (0.41) NAPRTKDM4E
SCHEMBL7719703 0.72 TSHR (0.35) KDM4E
SCHEMBL7537199 0.70 NAPRT (0.32) NAPRT
SCHEMBL7540472 0.70 MEN1 (0.33)
SCHEMBL10342969 0.69 HSP90AA1 (0.35) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002029021-A2 BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE LONZA AG (CH) 2002-04-11 WO disclosed