Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754536 | 0.89 | PAOX (0.37) | ALDH1A1TSHRKDM5APAOX | |
| SCHEMBL23230291 | 0.83 | MEN1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL211903 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM5APOLBPOLA1DNM1 | |
| SCHEMBL755507 | 0.80 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL1713084 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM5APOLBPOLA1 | |
| SCHEMBL8142273 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM5ADNM1ALOX15 | |
| SCHEMBL2304549 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM5ADNM1ALOX15 | |
| SCHEMBL31528799 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM5ADNM1ALOX15 | |
| SCHEMBL3963400 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM5ADNM1ALOX15 | |
| SCHEMBL1667458 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM5ADNM1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |