Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754054 | 0.89 | ALDH1A1 (0.39) | PAOXALDH1A1KDM5ATSHR | |
| SCHEMBL23230291 | 0.86 | MEN1 (0.32) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL755507 | 0.83 | TSHR (0.35) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4616554 | 0.79 | ALDH1A1 (0.54) | PAOXALDH1A1THRATHRBKDM5A | |
| SCHEMBL99297 | 0.79 | — | — | |
| SCHEMBL754145 | 0.78 | MEN1 (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL755895 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4019745 | 0.76 | PHF8 (0.39) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL24346148 | 0.76 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL3260392 | 0.76 | PHF8 (0.48) | PAOXALDH1A1THRATHRBCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |