SCHEMBL6497279

SCHEMBL6497279

C=CCOC(=O)N1CCC(OS(C)(=O)=O)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.40
PLG P00747 2/20 0.40
F2 P00734 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
GAA P10253 2/20 0.38
GPR119 Q8TDV5 1/20 0.38
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
TSHR P16473 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7540588 0.92 F10 (0.42) F10PLGF2L3MBTL1HTT
SCHEMBL31682843 0.92 F10 (0.42) F10PLGF2L3MBTL1HTT
SCHEMBL13978434 0.92 F10 (0.42) F10PLGF2L3MBTL1HTT
SCHEMBL31682777 0.85 F10 (0.35) F10PLGF2L3MBTL1HTT
SCHEMBL3022437 0.83 GAA (0.54) L3MBTL1HTTGAATP53TDP1
SCHEMBL31682828 0.81 GPR119 (0.37) F10PLGF2L3MBTL1HTT
SCHEMBL3248801 0.80 GPR119 (0.42) F10PLGF2L3MBTL1GAA
SCHEMBL17911431 0.79 TEAD1 (0.40) KMT2A
SCHEMBL19343639 0.79 ALDH1A1 (0.44) L3MBTL1GAAGPR119LMNAMAPK1
SCHEMBL5249314 0.78 GPR119 (0.45) L3MBTL1HTTGAAGPR119RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282796-A1 PENEM ANTIBACTERIALS AGAINST MYCOBACTERIAL PATHOGENS AND D,D- AND L,D TRANSPEPTIDASES THE JOHNS HOPKINS UNIVERSITY 2025-09-11 US disclosed
CN-118359620-A BRM selective degradation agent compound derivative and application thereof 南京再明医药有限公司 2024-07-19 CN disclosed
US-6969712-B2 Benzimidazole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-29 US disclosed
US-20040044056-A1 Benzimidazole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2004-03-04 US disclosed
EP-1342717-A1 BENZIMIDAZOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2003-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282796-A1 PENEM ANTIBACTERIALS AGAINST MYCOBACTERIAL PATHOGENS AND D,D- AND L,D TRANSPEPTIDASES PEPD, DNPEP, NAALAD2 F10 1695/4885PLG 217/4885F2 1658/4885
US-20040044056-A1 Benzimidazole derivatives GPR119, OPRL1, INSR F10 4147/4885PLG 3244/4885F2 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.