Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914161 | 0.88 | RXFP1 (0.52) | KDM4EALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL23259552 | 0.88 | RXFP1 (0.52) | KDM4EALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL18400201 | 0.87 | RXFP1 (0.54) | KDM4EALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL12292165 | 0.86 | RXFP1 (0.53) | KDM4EALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL29663621 | 0.85 | RXFP1 (0.55) | KDM4EALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL29702265 | 0.85 | RXFP1 (0.55) | KDM4ERXFP1MEN1KMT2APKM | |
| SCHEMBL15368377 | 0.85 | RXFP1 (0.59) | RXFP1MEN1KMT2ALMNAPOLB | |
| SCHEMBL29992092 | 0.85 | RXFP1 (0.59) | RXFP1MEN1KMT2ALMNAPOLB | |
| SCHEMBL222446 | 0.85 | RXFP1 (0.55) | KDM4ERXFP1MEN1KMT2APKM | |
| SCHEMBL30914162 | 0.85 | RXFP1 (0.50) | KDM4EALDH1A1RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742903-B1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2002-01-16 | — | — | EP | disclosed |