Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914161 | 1.00 | RXFP1 (0.52) | RXFP1POLBLMNAMETAP1IDO1 | |
| SCHEMBL7540602 | 0.88 | KDM4E (0.55) | RXFP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL29702265 | 0.83 | RXFP1 (0.55) | RXFP1POLBLMNAKDM4EBRD9 | |
| SCHEMBL29663621 | 0.83 | RXFP1 (0.55) | RXFP1POLBLMNAIDO1KDM4E | |
| SCHEMBL222446 | 0.83 | RXFP1 (0.55) | RXFP1POLBLMNAKDM4EBRD9 | |
| SCHEMBL15368377 | 0.83 | RXFP1 (0.59) | RXFP1POLBLMNAMETAP1IDO1 | |
| SCHEMBL29992092 | 0.83 | RXFP1 (0.59) | RXFP1POLBLMNAMETAP1IDO1 | |
| SCHEMBL30914162 | 0.82 | RXFP1 (0.50) | RXFP1POLBLMNAMETAP1IDO1 | |
| SCHEMBL23259553 | 0.82 | RXFP1 (0.50) | RXFP1POLBLMNAMETAP1IDO1 | |
| SCHEMBL30914166 | 0.82 | RXFP1 (0.50) | RXFP1POLBLMNAMETAP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077102-A1 | NOVEL ANTIPARASITIC COMPOUNDS AND METHODS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-22 | — | — | WO | disclosed |