Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222447 | 0.86 | G6PD (0.50) | ADRA1AADRA1BGRM6SLC7A5ALDH1A1 | |
| SCHEMBL6542697 | 0.84 | ALDH1A1 (0.46) | ADRA1AADRA1BGRM6SLC7A5ALDH1A1 | |
| SCHEMBL11080330 | 0.83 | GRM6 (0.40) | PARP1ADRA1AADRA1BGRM6SLC7A5 | |
| SCHEMBL7350764 | 0.83 | CA12 (0.38) | PARP1ADRA1AADRA1BGRM6SLC7A5 | |
| SCHEMBL31011138 | 0.83 | G6PD (0.55) | GRM6SLC7A5ALDH1A1HSD17B10KDM4E | |
| SCHEMBL27887677 | 0.83 | CYP2D6 (0.45) | ADRA1AADRA1BGRM6SLC7A5ALDH1A1 | |
| SCHEMBL2940954 | 0.83 | G6PD (0.55) | GRM6SLC7A5ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29077113 | 0.83 | GRM6 (0.41) | PARP1ADRA1AADRA1BGRM6IRAK4 | |
| SCHEMBL15771897 | 0.81 | GRM6 (0.40) | GRM6SLC7A5ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29058056 | 0.81 | CA2 (0.38) | PARP1ADRA1AADRA1BGRM6SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742903-B1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2002-01-16 | — | — | EP | disclosed |