Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484219 | 0.87 | ALDH1A1 (0.39) | ALDH1A1POLBCNR2CNR1GAA | |
| SCHEMBL27756470 | 0.84 | MAPK14 (0.36) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL756036 | 0.83 | MAPK14 (0.36) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL756034 | 0.83 | TP53 (0.39) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL753007 | 0.82 | MAPK14 (0.35) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL756035 | 0.82 | LMNA (0.35) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL755219 | 0.79 | CNR2 (0.44) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL10290766 | 0.79 | CNR2 (0.44) | ALDH1A1POLBCNR2GPR55CNR1 | |
| SCHEMBL752953 | 0.77 | CCNT1 (0.35) | MMP1CNR2GPR55CNR1LMNA | |
| SCHEMBL18531594 | 0.77 | CNR2 (0.42) | ALDH1A1POLBCNR2GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |