Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756034 | 0.84 | TP53 (0.39) | LMNANPSR1THRBTP53MAPT | |
| SCHEMBL754069 | 0.82 | MMP3 (0.41) | LMNANPSR1MAPTCNR1CNR2 | |
| SCHEMBL2484219 | 0.81 | ALDH1A1 (0.39) | LMNATHRBTP53MAPTCNR1 | |
| SCHEMBL27756470 | 0.78 | MAPK14 (0.36) | LMNANPSR1THRBTP53MAPT | |
| SCHEMBL756036 | 0.77 | MAPK14 (0.36) | LMNANPSR1THRBTP53MAPT | |
| SCHEMBL753007 | 0.77 | MAPK14 (0.35) | LMNANPSR1THRBCNR1CNR2 | |
| SCHEMBL752953 | 0.72 | CCNT1 (0.35) | LMNACNR1CNR2SMN1; SMN2GPR55 | |
| SCHEMBL755566 | 0.65 | L3MBTL1 (0.38) | LMNATP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL6810475 | 0.65 | EGLN1 (0.42) | LMNANPSR1THRBTP53MAPT | |
| SCHEMBL2486131 | 0.64 | KLKB1 (0.49) | LMNANPSR1THRBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |